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Atherosclerosis (AS) is a chronic inflammatory disease. Briefly, endothelial injury is the first step of AS that changes the permeability of endothelium and allows LDL-C particles into the arterial cell. Then endothelial cells secrete pro-inflammatory factors,such as monocyte chemotactic protein (MCP-1) and interleukins, e.g., IL-6, to stimulate circulating monocytes adhering to endothelial cells and migrating into subendothelial(本文共计1页)......[继续阅读本文]

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