来源:《Chinese Herbal Medicines》2019年第01期  作者:Ying Zhao;Liang Le;Yue-qiang Song;Li-xin Qi;Hui Fu;Xue Bai;Si-guang Li;Xin-sheng Nan;Ke-ping Hu;
选择字号

Positive effects of low dose IMPX977 on Rett syndrome related MeCP2 targeted-genes

收藏本文  分享

Objective: To investigate the effect of IMPX977 on MeCP2 targeted-genes and the feasibility of IMPX977 acting as a therapeutic candidate drug for Rett syndrome by genomewide transcription profiling.Methods: Rats' cortex of control group, IMPX977-treated low-dose group(10 mg/kg), and IMPX977-treated high-dose group(30 mg/kg) were collected and RNA was extracted from the tissues. Then, RNA was subjected to RNA-sequencing. Gene ontology(GO) and kyoto encyclopedia of genes and genomes(KEGG)were used(本文共计6页)......[继续阅读本文]

下载阅读本文订阅本刊

图书推荐

    相关文章推荐

    看看这些杂志对你有没有帮助...

    更多杂志>>