来源:《Cell Research》2005年第06期  作者:Andrea K. PERRY
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The host type I interferon response to viral and bacterial infections

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Introduction The type I interferons (IFN) were the first cytokinesdiscovered and named for their potent ability to “inter-fere” with viral replication [1]. In 1957, Isaacs andLindenmann reported a secreted factor termed “interferon”that could induce a virus-resistant state in chick cells afterinfluenza virus infection [1]. The type I IFN family con-sists of multiple IFNα members, single IFNβ, ε, κ, and ωsubtypes, as well as δ and τ subtypes found in pig andovine respectively [2]. These cytokines(本文共计16页)......[继续阅读本文]

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