来源:《Cell Research》2005年第06期  作者:
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Identification, characteristic and phylogenetic analysis of type II DNA topoisomerase gene in Giardia lamblia

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INTRODUCTION DNA topoisomerases, found in eukaryotes andprokaryotes, are enzymes that have evolved to solve thetopological problems associated with DNA metabolismssuch as transcription, replication, packing and unpackingof DNA in the cell [1]. They are classified as type topoisomerases if they create single-stranded breaks inDNA duplex or as type II topoisomerases if doublestranded breaks are created.Type II DNA topoisomerases are a class of ubiquitousenzymes found in almost all the living cells(本文共计9页)......[继续阅读本文]

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