来源:《Cell Research》2007年第07期  作者:
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Generation and selection of immunized Fab phage display library against human B cell lymphoma

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The approval of using monoclonal antibodies as a targeted therapy in the management of patients with B cell lym-phoma has led to new treatment options for this group of patients. Production of monoclonal antibodies by the traditionalhybridoma technology is costly, and the resulting murine antibodies often have the disadvantage of triggering humananti-mouse antibody (HAMA) response. Therefore recombinant Fab antibodies generated by the phage display technol-ogy can be a suitable alternative i(本文共计11页)

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